Many new drugs have come out into the mainstream market which claim to reduce drastically if not completely cure snoring. For those few for whom all these medicenes have failed, doctors suggest surgery as the drastic last resort.
But what do you do, if you thoroughly dislike medicenes and are scared of the knife. Are you doomed to be the laughing stock for snoring for the rest of youy life?
This can probably drive you nuts if you were unaware that herbs are very effective in curing snoring. No. This is not a mere sales gimmick. You can stop snoring through herbal cures.
Of the various methods to prevent or completely stop snoring that are out there today, you must agree that natural supplements are much safer than drugs which are normally prescribed.
Please note that natural is not synonymous with without recommendation. There are certain natural substances that can hamper the course of action of other drugs and need to be avoided since they can be intoxicating.
Advice of a medical expert must be sought before administering any of these supplements. Else, conduct researches yourself.
This is more strongly adviced if you are already under medication or are allergic to certain things that can be triggered by these supplements.
Much like their artificial counterparts, even herbal drugs must be taken only in carefully prescribed doses.
There are people who have an aversion to taking artificial medicenes and believe that natural supplements are the way to go to gracefully treat the human body.
It is because of this that knowledge of natural alternatives to cure snoring is sought after. A large portion of people will prefer it over even medicenes that are readily available in the market and have natural ingredients.
Aromapathy is another well-known cure for snoring. This method uses certain oils to relax the airway.The anti-inflamatory action of these oils is taken advantage of here.You may also use these oils through sprays or mouth rinses.
Though this method is simple, it is strongly discouraged for people with asthma or any previous breathing problems. Avoid contact with eyes. Consult a doctor immediately if it accidentally falls into the eyes.
Herbal supplements packaged in the form of tablets are also widely used. These help clearing mucus in the throat and helps relaxing the air pipe. Mucous causes blocking of the insides of the throat which is normally ignored by the person who snores. This produces a contraction of the windpipe which further leads to snoring. These tablets help alleviate these problems.
Hungry for more information on this interesting cure? Search engines can be your friend and guide in this venture. Search for then with apt keywords like “Herbal snoring cure” or “Natural cure for snoring” to find millions of pages on the topic.
A homeopathic professional is best suited to suggest what you can take and what you must avoid.
There are thousands of success stories where people have successfully overcome snoring. Try it yourself and join them.
A word of caution: What may suit others may not suit you. One man’s food is another’s poison.
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Saturday, October 8, 2011
Juriste
►► Droit-et-sciences-politiques -- juriste,Dans le monde de l’entreprise, le Juriste occupe également de nos jours, une place prépondérante ......
Production immobilisée comptabilité
►► Comptabilité -- Production immobilisée comptabilité,Ce compte est un compte de produit qui a comme numéro 72 dans le plan comptable......
Point g
►► Psychologie -- Le point G féminin, ou point de Gräfenberg, est une zone érogène située dans la paroi antérieure du vagin......
Contraception stérilet
►► Gynéco-obstétrique -- Contraception stérilet, Le stérilet est une méthode contraceptive très utilisée .......
LES ENTORSES DU GENOU
►► Medecine_et_sport -- Les entorses du genou sont des lésions traumatiques de l’appareil capsulo ligamentaire du genou sans déplacement des surfaces articulaires...
Facture pro forma comptabilité
►► Comptabilité -- Facture pro forma comptabilité:La facture pro forma est une facture provisoire qui n’a pas de valeur comptable.....
Exhibition couple
►► Psychologie -- Exhibition couple, Tout couple amoureux a ses moments d’exhibitionnisme. La femme aime offrir son sexe mis en scène ......
La femme face aux violences conjugales
►► Psychologie -- La femme face à la violence conjugale:La violence conjugale est un processus évolutif au cours duquel un partenaire exerce une domination...
Frais de notaire
►► Droit-et-sciences-politiques -- Il s'agit des frais exposés par le notaire et indispensables à rendre la vente plus sûre ......
Licenciement
►► Droit-et-sciences-politiques -- licenciement,Le licenciement est la mesure par laquelle, agissant d'une façon unilatérale,un employeur décide de mettre fin au contrat ......
LA PEAU
►► Dermatologie -- La peau: On ne naît pas allergique à un produit cosmétique, on le devient grâce à la mémoire de la peau....
Femme frigide et frigidité
►► Sexualité -- Femme frigide et frigidité, La frigidité est l'impossibilité pour une femme d'éprouver une jouissance normale au cours des rapports sexuels....
►► Droit-et-sciences-politiques -- juriste,Dans le monde de l’entreprise, le Juriste occupe également de nos jours, une place prépondérante ......
Production immobilisée comptabilité
►► Comptabilité -- Production immobilisée comptabilité,Ce compte est un compte de produit qui a comme numéro 72 dans le plan comptable......
Point g
►► Psychologie -- Le point G féminin, ou point de Gräfenberg, est une zone érogène située dans la paroi antérieure du vagin......
Contraception stérilet
►► Gynéco-obstétrique -- Contraception stérilet, Le stérilet est une méthode contraceptive très utilisée .......
LES ENTORSES DU GENOU
►► Medecine_et_sport -- Les entorses du genou sont des lésions traumatiques de l’appareil capsulo ligamentaire du genou sans déplacement des surfaces articulaires...
Facture pro forma comptabilité
►► Comptabilité -- Facture pro forma comptabilité:La facture pro forma est une facture provisoire qui n’a pas de valeur comptable.....
Exhibition couple
►► Psychologie -- Exhibition couple, Tout couple amoureux a ses moments d’exhibitionnisme. La femme aime offrir son sexe mis en scène ......
La femme face aux violences conjugales
►► Psychologie -- La femme face à la violence conjugale:La violence conjugale est un processus évolutif au cours duquel un partenaire exerce une domination...
Frais de notaire
►► Droit-et-sciences-politiques -- Il s'agit des frais exposés par le notaire et indispensables à rendre la vente plus sûre ......
Licenciement
►► Droit-et-sciences-politiques -- licenciement,Le licenciement est la mesure par laquelle, agissant d'une façon unilatérale,un employeur décide de mettre fin au contrat ......
LA PEAU
►► Dermatologie -- La peau: On ne naît pas allergique à un produit cosmétique, on le devient grâce à la mémoire de la peau....
Femme frigide et frigidité
►► Sexualité -- Femme frigide et frigidité, La frigidité est l'impossibilité pour une femme d'éprouver une jouissance normale au cours des rapports sexuels....
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Arginine
From Wikipedia, the free encyclopedia
It has been suggested that Arginine pyroglutamate be merged into this article or section. (Discuss) Proposed since April 2010.
L-Arginine
IUPAC name[hide]
(S)-2-Amino-5-guanidinopentanoic acid
Other names[hide]
Arginine
Identifiers
CAS number 74-79-3
PubChem 6322
ChemSpider 227
UNII 94ZLA3W45F
KEGG C02385
ChEBI CHEBI:29016
ChEMBL CHEMBL1485
IUPHAR ligand 721
Jmol-3D images Image 1
Image 2
SMILES
[show]
InChI
[show]
Properties
Molecular formula C6H14N4O2
Molar mass 174.2 g mol−1
Supplementary data page
Structure and
properties n, εr, etc.
Thermodynamic
data Phase behaviour
Solid, liquid, gas
Spectral data UV, IR, NMR, MS
(what is this?) (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references
Arginine (abbreviated as Arg or R)[1] is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that codify for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.[2] Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them.[3] There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns.[citation needed] Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.
In general, most people do not need to take arginine supplements because the body usually produces enough.[4]
Contents [hide]
1 Structure
2 Sources
2.1 Dietary sources
2.2 Biosynthesis
3 Function
3.1 Proteins
3.2 Precursor
3.3 Treatment of dentin hypersensitivity
3.4 Treatment of herpes simplex virus
3.5 Possible increased risk of death after supplementation following heart attack
4 Potential medical uses
4.1 Lung inflammation and asthma
4.2 Growth hormone
4.3 MELAS syndrome
4.4 Sepsis
4.5 Malate salt
4.6 Pre-eclampsia
5 See also
6 References
7 External links
[edit]Structure
The amino acid side-chain of arginine consists of a 3-carbon aliphatic straight chain, the distal end of which is capped by a complex guanidinium group.
Delocalization of charge in guanidinium group of L-Arginine
With a pKa of 12.48, the guanidinium group is positively charged in neutral, acidic and even most basic environments, and thus imparts basic chemical properties to arginine. Because of the conjugation between the double bond and the nitrogen lone pairs, the positive charge is delocalized, enabling the formation of multiple H-bonds.
[edit]Sources
[edit]Dietary sources
Arginine is a conditionally nonessential amino acid, meaning most of the time it can be manufactured by the human body, and does not need to be obtained directly through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some must still be consumed through diet. Individuals who have poor nutrition or certain physical conditions may be advised to increase their intake of foods containing arginine. Arginine is found in a wide variety of foods, including[5]:
Animal sources
dairy products (e.g., cottage cheese, ricotta, milk, yogurt, whey protein drinks), beef, pork (e.g., bacon, ham), gelatin , poultry (e.g. chicken and turkey light meat), wild game (e.g. pheasant, quail), seafood (e.g., halibut, lobster, salmon, shrimp, snails, tuna)
Plant sources
wheat germ and flour, buckwheat, granola, oatmeal, peanuts, nuts (coconut, pecans, cashews, walnuts, almonds, Brazil nuts, hazelnuts, pinenuts), seeds (pumpkin, sesame, sunflower), chick peas, cooked soybeans, Phalaris canariensis (canaryseed or ALPISTE)
[edit]Biosynthesis
Arginine is synthesized from citrulline by the sequential action of the cytosolic enzymes argininosuccinate synthetase (ASS) and argininosuccinate lyase (ASL). In terms of energy, this is costly, as the synthesis of each molecule of argininosuccinate requires hydrolysis of adenosine triphosphate (ATP) to adenosine monophosphate (AMP), i.e., two ATP equivalents.
Citrulline can be derived from multiple sources:
from arginine via nitric oxide synthase (NOS)
from ornithine via catabolism of proline or glutamine/glutamate
from asymmetric dimethylarginine (ADMA) via DDAH
The pathways linking arginine, glutamine, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.
On a whole-body basis, synthesis of arginine occurs principally via the intestinal–renal axis, wherein epithelial cells of the small intestine, which produce citrulline primarily from glutamine and glutamate, collaborate with the proximal tubule cells of the kidney, which extract citrulline from the circulation and convert it to arginine, which is returned to the circulation. As a consequence, impairment of small bowel or renal function can reduce endogenous arginine synthesis, thereby increasing the dietary requirement.
Synthesis of arginine from citrulline also occurs at a low level in many other cells, and cellular capacity for arginine synthesis can be markedly increased under circumstances that also induce iNOS. Thus, citrulline, a coproduct of the NOS-catalyzed reaction, can be recycled to arginine in a pathway known as the citrulline-NO or arginine-citrulline pathway. This is demonstrated by the fact that in many cell types, citrulline can substitute for arginine to some degree in supporting NO synthesis. However, recycling is not quantitative because citrulline accumulates along with nitrate and nitrite, the stable end-products of NO, in NO-producing cells.[6]
[edit]Function
Arginine plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, and the release of hormones.[2][7][8] Arginine taken in combination with proanthocyanidins[9] or yohimbine,[10] has also been used as a treatment for erectile dysfunction.
The benefits and functions attributed to oral supplementation of L-arginine include:
Precursor for the synthesis of nitric oxide (NO)[11]
Reduces healing time of injuries (particularly bone)[7][8]
Quickens repair time of damaged tissue[7][8]
Helps decrease blood pressure[12][13]
[edit]Proteins
The distributing basics of the moderate structure found in geometry, charge distribution and ability to form multiple H-bonds make arginine ideal for binding negatively charged groups. For this reason, arginine prefers to be on the outside of the proteins where it can interact with the polar environment.
Incorporated in proteins, arginine can also be converted to citrulline by PAD enzymes. In addition, arginine can be methylated by protein methyltransferases.
[edit]Precursor
Arginine is the immediate precursor of NO, urea, ornithine, and agmatine; is necessary for the synthesis of creatine; and can also be used for the synthesis of polyamines (mainly through ornithine and to a lesser degree through agmatine), citrulline, and glutamate. As a precursor of nitric oxide, arginine may have a role in the treatment of some conditions where vasodilation is required.[2] The presence of asymmetric dimethylarginine (ADMA), a close relative, inhibits the nitric oxide reaction; therefore, ADMA is considered a marker for vascular disease, just as L-arginine is considered a sign of a healthy endothelium.
[edit]Treatment of dentin hypersensitivity
Arginine (8%) in dental products (e.g., toothpaste) provides effective relief from sensitive teeth by depositing a dentin-like mineral, containing calcium and phosphate, within the dentin tubules and in a protective layer on the dentin surface.[14]
[edit]Treatment of herpes simplex virus
An unproven claim is that a low ratio of arginine to lysine may be of benefit in the treatment of herpes simplex virus. For more information, refer to Herpes - Treatment also see journal article.[15]
[edit]Possible increased risk of death after supplementation following heart attack
A clinical trial found that patients taking an L-arginine supplement following a heart attack found no change in the heart's vascular tone or decrease in the symptoms of congestive heart failure (the hearts' ability to pump). In fact, six more patients who were taking L-arginine died than those taking a placebo resulting in early termination of the study with the recommendation that the supplement not be used by heart attack patients.[16][17][18] Despite these findings, the supplement is still widely marketed as "beneficial" for the heart.
[edit]Potential medical uses
[edit]Lung inflammation and asthma
The Mayo Clinic web page on L-arginine reports that inhalation of L-arginine can increase lung inflammation and worsen asthma.[19]
[edit]Growth hormone
Arginine may stimulate the secretion of growth hormone,[20] and is used in growth hormone stimulation tests.[21]
[edit]MELAS syndrome
Several trials delved into effects of L-arginine in MELAS syndrome, a mitochondrial disease.[22][23][24][25]
[edit]Sepsis
Cellular arginine biosynthetic capacity determined by activity of argininosuccinate synthetase (AS) is induced by the same mediators of septic response — endotoxin and cytokines — that induce nitric oxide synthase (NOS), the enzyme responsible for nitric oxide synthesis.[26]
[edit]Malate salt
The malate salt of arginine can also be used during the treatment of alcoholic hepatitis and advanced cirrhosis.[27]
[edit]Pre-eclampsia
A preliminary study of supplementation with L-arginine and antioxidant vitamins showed that this combination may help to combat abnormally high blood pressure during high risk pregnancies.[28]
[edit]See also
AAKG
canavanine and canaline are toxic analogues of arginine and ornithine
[edit]References
^ IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. "Nomenclature and Symbolism for Amino Acids and Peptides". Recommendations on Organic & Biochemical Nomenclature, Symbols & Terminology etc. Retrieved 2007-05-17.
^ a b c Tapiero, H.; et al. (November 2002). "L-Arginine". Biomedicine and Pharmacotherapy 56 (9): 439–445 REVIEW. doi:10.1161/hc3301.094910. PMID 12481980.
^ Wu, G.; et al. (August 2004). "Arginine deficiency in preterm infants: biochemical mechanisms and nutritional implications". Journal of Nutritional Biochemistry 15 (8): 332–451 REVIEW. doi:10.1016/j.jnutbio.2003.11.010. PMID 15302078.
^ Mayo Clinic
^ "L-Arginine Supplements Nitric Oxide Scientific Studies Food Sources". Retrieved 2007-02-20.
^ Morris Jr SM (October 2004). "Enzymes of arginine metabolism.". The Journal of nutrition 134 (10 Suppl): 2743S–2747S. PMID 15465778.
^ a b c Stechmiller, J.K.; et al. (February 2005). "Arginine supplementation and wound healing". Nutrition in Clinical Practice 20 (13): 52–61 REVIEW. doi:10.1177/011542650502000152. PMID 16207646.
^ a b c Witte, M.B.; Barbul, A (Nov-Dec 2003). "Arginine physiology and its implication for wound healing". Wound Repair and Regeneration 11 (6): 419–423 REVIEW. doi:10.1046/j.1524-475X.2003.11605.x. PMID 14617280.
^ Stanislavov R., Nikolova V (2003). "Treatment of Erectile Dysfunction with Pycnogenol and L-arginine". Journal of Sex and Marital Therapy 29 (3): 207–213. doi:10.1080/00926230390155104. PMID 12851125.
^ Lebret, T.; Hervéa, J. M.; Gornyb, P.; Worcelc, M.; Botto, H. (2002). "Efficacy and Safety of a Novel Combination of L-Arginine Glutamate and Yohimbine Hydrochloride: A New Oral Therapy for Erectile Dysfunction". European Urology 41 (6): 608–613. doi:10.1016/S0302-2838(02)00175-6. PMID 12074777.
^ Andrew, P.J.; Myer, B. (August 15 1999). "Enzymatic function of nitric oxide synthases". Cardiovascular Research 43 (3): 521–531 REVIEW. doi:10.1016/S0008-6363(99)00115-7. PMID 10690324. [1]
^ Gokce, N.. (October 2004). "L-Arginine and hypertension". Journal of Nutrition 134 (10 Suppl): 2807S–2811S REVIEW. PMID 15465790.
^ Rajapakse, N.W.; et al. (December 2008). "Exogenous L-arginine ameliorates angiotensin II-induced hypertension and renal damage in rats". Hypertension 52 (6): 1084–1090. doi:10.1161/HYPERTENSIONAHA.108.114298. PMC 2680209. PMID 18981330. Retrieved 2009-11-29. [2]
^ Petrou, I.; et al. (2009). "A breakthrough therapy for dentin hypersensitivity: how dental products containing 8% arginine and calcium carbonate work to deliver effective relief of sensitive teeth.". The Journal of Clinical Dentisry 20 (1): 23–31. PMID 19489189.
^ Takeshi Naito, Hiroshi Irie, Kazuko Tsujimoto, Keiko Ikeda, Tsutomu Arakawa, A. Hajime Koyama (April 2009). "Antiviral effect of arginine against herpes simplex virus type 1". International Journal of Molecular Medicine 23 (4): 495–499. doi:10.3892/ijmm_00000156. PMID 19288025. Retrieved 2010-10-18.
^ Medical College of Georgia. "Diabetes Makes It Hard For Blood Vessels To Relax." ScienceDaily 1 February 2008. 1 February 2008
^ Schulman SP, Becker LC, Kass DA, Champion HC, Terrin ML, Forman S, Ernst KV, Kelemen MD et al. (January 2006). "L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.". JAMA : the journal of the American Medical Association 295 (1): 58–64. doi:10.1001/jama.295.1.58. PMID 16391217.
^ This study has been discussed in some detail in : "Reverse Heart Disease Now" by Stephen T Sinatra MD and James C Roberts MD, publ. Wiley 2006 ISBN 0-471-74704-1 at pp 111-113.
^ Sapienza MA, Kharitonov SA, Horvath I, Chung KF, Barnes PJ. "Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects." Thorax. 1998 Mar;53(3):172-5.
^ Alba-Roth J, Müller O, Schopohl J, von Werder K (1988). "Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion". J Clin Endocrinol Metab 67 (6): 1186–9. doi:10.1210/jcem-67-6-1186. PMID 2903866.
^ U.S. National Library of Medicine (September 2009). Growth hormone stimulation test
^ Koga Y, Akita Y, Junko N, Yatsuga S, Povalko N, Fukiyama R, Ishii M, Matsuishi T (June 2006). "Endothelial dysfunction in MELAS improved by l-arginine supplementation". Neurology 66 (11): 1766–9. doi:10.1212/01.wnl.0000220197.36849.1e. PMID 16769961.
^ Koga Y (November 2008). "[L-arginine therapy on MELAS]" (in Japanese). Rinsho Shinkeigaku 48 (11): 1010–2. PMID 19198147.
^ Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Katayama K, Matsuishi T (2007). "MELAS and L-arginine therapy". Mitochondrion 7 (1–2): 133–9. doi:10.1016/j.mito.2006.11.006. PMID 17276739.
^ Finsterer J (November 2009). "Management of mitochondrial stroke-like-episodes". Eur. J. Neurol. 16 (11): 1178–84. doi:10.1111/j.1468-1331.2009.02789.x. PMID 19780807.
^ MORRIS SM (1995). ROLE OF ARGININE SYNTHESIS IN SURGICAL SEPSIS. Retrieved 2010-02-22.
^ Tissot-Favre A, Brette R (May–June 1970). "Therapeutic effects of arginine malate in alcoholic cirrhosis". Therapie 25 (3): 629–33. PMID 5431854.
^ Vadillo-Ortega F et al. (2011). "Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medical food on pre-eclampsia in high risk population: randomised controlled trial". British Medical Journal 342: d2901–d2901. doi:10.1136/bmj.d2901.
[edit]External links
Wikimedia Commons has media related to: arginine
NIST Chemistry Webbook
Mayo Clinic discussion of Arginine.
National Institute of Health discussion of Arginine.
From Wikipedia, the free encyclopedia
It has been suggested that Arginine pyroglutamate be merged into this article or section. (Discuss) Proposed since April 2010.
L-Arginine
IUPAC name[hide]
(S)-2-Amino-5-guanidinopentanoic acid
Other names[hide]
Arginine
Identifiers
CAS number 74-79-3
PubChem 6322
ChemSpider 227
UNII 94ZLA3W45F
KEGG C02385
ChEBI CHEBI:29016
ChEMBL CHEMBL1485
IUPHAR ligand 721
Jmol-3D images Image 1
Image 2
SMILES
[show]
InChI
[show]
Properties
Molecular formula C6H14N4O2
Molar mass 174.2 g mol−1
Supplementary data page
Structure and
properties n, εr, etc.
Thermodynamic
data Phase behaviour
Solid, liquid, gas
Spectral data UV, IR, NMR, MS
(what is this?) (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references
Arginine (abbreviated as Arg or R)[1] is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that codify for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.[2] Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them.[3] There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns.[citation needed] Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.
In general, most people do not need to take arginine supplements because the body usually produces enough.[4]
Contents [hide]
1 Structure
2 Sources
2.1 Dietary sources
2.2 Biosynthesis
3 Function
3.1 Proteins
3.2 Precursor
3.3 Treatment of dentin hypersensitivity
3.4 Treatment of herpes simplex virus
3.5 Possible increased risk of death after supplementation following heart attack
4 Potential medical uses
4.1 Lung inflammation and asthma
4.2 Growth hormone
4.3 MELAS syndrome
4.4 Sepsis
4.5 Malate salt
4.6 Pre-eclampsia
5 See also
6 References
7 External links
[edit]Structure
The amino acid side-chain of arginine consists of a 3-carbon aliphatic straight chain, the distal end of which is capped by a complex guanidinium group.
Delocalization of charge in guanidinium group of L-Arginine
With a pKa of 12.48, the guanidinium group is positively charged in neutral, acidic and even most basic environments, and thus imparts basic chemical properties to arginine. Because of the conjugation between the double bond and the nitrogen lone pairs, the positive charge is delocalized, enabling the formation of multiple H-bonds.
[edit]Sources
[edit]Dietary sources
Arginine is a conditionally nonessential amino acid, meaning most of the time it can be manufactured by the human body, and does not need to be obtained directly through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some must still be consumed through diet. Individuals who have poor nutrition or certain physical conditions may be advised to increase their intake of foods containing arginine. Arginine is found in a wide variety of foods, including[5]:
Animal sources
dairy products (e.g., cottage cheese, ricotta, milk, yogurt, whey protein drinks), beef, pork (e.g., bacon, ham), gelatin , poultry (e.g. chicken and turkey light meat), wild game (e.g. pheasant, quail), seafood (e.g., halibut, lobster, salmon, shrimp, snails, tuna)
Plant sources
wheat germ and flour, buckwheat, granola, oatmeal, peanuts, nuts (coconut, pecans, cashews, walnuts, almonds, Brazil nuts, hazelnuts, pinenuts), seeds (pumpkin, sesame, sunflower), chick peas, cooked soybeans, Phalaris canariensis (canaryseed or ALPISTE)
[edit]Biosynthesis
Arginine is synthesized from citrulline by the sequential action of the cytosolic enzymes argininosuccinate synthetase (ASS) and argininosuccinate lyase (ASL). In terms of energy, this is costly, as the synthesis of each molecule of argininosuccinate requires hydrolysis of adenosine triphosphate (ATP) to adenosine monophosphate (AMP), i.e., two ATP equivalents.
Citrulline can be derived from multiple sources:
from arginine via nitric oxide synthase (NOS)
from ornithine via catabolism of proline or glutamine/glutamate
from asymmetric dimethylarginine (ADMA) via DDAH
The pathways linking arginine, glutamine, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.
On a whole-body basis, synthesis of arginine occurs principally via the intestinal–renal axis, wherein epithelial cells of the small intestine, which produce citrulline primarily from glutamine and glutamate, collaborate with the proximal tubule cells of the kidney, which extract citrulline from the circulation and convert it to arginine, which is returned to the circulation. As a consequence, impairment of small bowel or renal function can reduce endogenous arginine synthesis, thereby increasing the dietary requirement.
Synthesis of arginine from citrulline also occurs at a low level in many other cells, and cellular capacity for arginine synthesis can be markedly increased under circumstances that also induce iNOS. Thus, citrulline, a coproduct of the NOS-catalyzed reaction, can be recycled to arginine in a pathway known as the citrulline-NO or arginine-citrulline pathway. This is demonstrated by the fact that in many cell types, citrulline can substitute for arginine to some degree in supporting NO synthesis. However, recycling is not quantitative because citrulline accumulates along with nitrate and nitrite, the stable end-products of NO, in NO-producing cells.[6]
[edit]Function
Arginine plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, and the release of hormones.[2][7][8] Arginine taken in combination with proanthocyanidins[9] or yohimbine,[10] has also been used as a treatment for erectile dysfunction.
The benefits and functions attributed to oral supplementation of L-arginine include:
Precursor for the synthesis of nitric oxide (NO)[11]
Reduces healing time of injuries (particularly bone)[7][8]
Quickens repair time of damaged tissue[7][8]
Helps decrease blood pressure[12][13]
[edit]Proteins
The distributing basics of the moderate structure found in geometry, charge distribution and ability to form multiple H-bonds make arginine ideal for binding negatively charged groups. For this reason, arginine prefers to be on the outside of the proteins where it can interact with the polar environment.
Incorporated in proteins, arginine can also be converted to citrulline by PAD enzymes. In addition, arginine can be methylated by protein methyltransferases.
[edit]Precursor
Arginine is the immediate precursor of NO, urea, ornithine, and agmatine; is necessary for the synthesis of creatine; and can also be used for the synthesis of polyamines (mainly through ornithine and to a lesser degree through agmatine), citrulline, and glutamate. As a precursor of nitric oxide, arginine may have a role in the treatment of some conditions where vasodilation is required.[2] The presence of asymmetric dimethylarginine (ADMA), a close relative, inhibits the nitric oxide reaction; therefore, ADMA is considered a marker for vascular disease, just as L-arginine is considered a sign of a healthy endothelium.
[edit]Treatment of dentin hypersensitivity
Arginine (8%) in dental products (e.g., toothpaste) provides effective relief from sensitive teeth by depositing a dentin-like mineral, containing calcium and phosphate, within the dentin tubules and in a protective layer on the dentin surface.[14]
[edit]Treatment of herpes simplex virus
An unproven claim is that a low ratio of arginine to lysine may be of benefit in the treatment of herpes simplex virus. For more information, refer to Herpes - Treatment also see journal article.[15]
[edit]Possible increased risk of death after supplementation following heart attack
A clinical trial found that patients taking an L-arginine supplement following a heart attack found no change in the heart's vascular tone or decrease in the symptoms of congestive heart failure (the hearts' ability to pump). In fact, six more patients who were taking L-arginine died than those taking a placebo resulting in early termination of the study with the recommendation that the supplement not be used by heart attack patients.[16][17][18] Despite these findings, the supplement is still widely marketed as "beneficial" for the heart.
[edit]Potential medical uses
[edit]Lung inflammation and asthma
The Mayo Clinic web page on L-arginine reports that inhalation of L-arginine can increase lung inflammation and worsen asthma.[19]
[edit]Growth hormone
Arginine may stimulate the secretion of growth hormone,[20] and is used in growth hormone stimulation tests.[21]
[edit]MELAS syndrome
Several trials delved into effects of L-arginine in MELAS syndrome, a mitochondrial disease.[22][23][24][25]
[edit]Sepsis
Cellular arginine biosynthetic capacity determined by activity of argininosuccinate synthetase (AS) is induced by the same mediators of septic response — endotoxin and cytokines — that induce nitric oxide synthase (NOS), the enzyme responsible for nitric oxide synthesis.[26]
[edit]Malate salt
The malate salt of arginine can also be used during the treatment of alcoholic hepatitis and advanced cirrhosis.[27]
[edit]Pre-eclampsia
A preliminary study of supplementation with L-arginine and antioxidant vitamins showed that this combination may help to combat abnormally high blood pressure during high risk pregnancies.[28]
[edit]See also
AAKG
canavanine and canaline are toxic analogues of arginine and ornithine
[edit]References
^ IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. "Nomenclature and Symbolism for Amino Acids and Peptides". Recommendations on Organic & Biochemical Nomenclature, Symbols & Terminology etc. Retrieved 2007-05-17.
^ a b c Tapiero, H.; et al. (November 2002). "L-Arginine". Biomedicine and Pharmacotherapy 56 (9): 439–445 REVIEW. doi:10.1161/hc3301.094910. PMID 12481980.
^ Wu, G.; et al. (August 2004). "Arginine deficiency in preterm infants: biochemical mechanisms and nutritional implications". Journal of Nutritional Biochemistry 15 (8): 332–451 REVIEW. doi:10.1016/j.jnutbio.2003.11.010. PMID 15302078.
^ Mayo Clinic
^ "L-Arginine Supplements Nitric Oxide Scientific Studies Food Sources". Retrieved 2007-02-20.
^ Morris Jr SM (October 2004). "Enzymes of arginine metabolism.". The Journal of nutrition 134 (10 Suppl): 2743S–2747S. PMID 15465778.
^ a b c Stechmiller, J.K.; et al. (February 2005). "Arginine supplementation and wound healing". Nutrition in Clinical Practice 20 (13): 52–61 REVIEW. doi:10.1177/011542650502000152. PMID 16207646.
^ a b c Witte, M.B.; Barbul, A (Nov-Dec 2003). "Arginine physiology and its implication for wound healing". Wound Repair and Regeneration 11 (6): 419–423 REVIEW. doi:10.1046/j.1524-475X.2003.11605.x. PMID 14617280.
^ Stanislavov R., Nikolova V (2003). "Treatment of Erectile Dysfunction with Pycnogenol and L-arginine". Journal of Sex and Marital Therapy 29 (3): 207–213. doi:10.1080/00926230390155104. PMID 12851125.
^ Lebret, T.; Hervéa, J. M.; Gornyb, P.; Worcelc, M.; Botto, H. (2002). "Efficacy and Safety of a Novel Combination of L-Arginine Glutamate and Yohimbine Hydrochloride: A New Oral Therapy for Erectile Dysfunction". European Urology 41 (6): 608–613. doi:10.1016/S0302-2838(02)00175-6. PMID 12074777.
^ Andrew, P.J.; Myer, B. (August 15 1999). "Enzymatic function of nitric oxide synthases". Cardiovascular Research 43 (3): 521–531 REVIEW. doi:10.1016/S0008-6363(99)00115-7. PMID 10690324. [1]
^ Gokce, N.. (October 2004). "L-Arginine and hypertension". Journal of Nutrition 134 (10 Suppl): 2807S–2811S REVIEW. PMID 15465790.
^ Rajapakse, N.W.; et al. (December 2008). "Exogenous L-arginine ameliorates angiotensin II-induced hypertension and renal damage in rats". Hypertension 52 (6): 1084–1090. doi:10.1161/HYPERTENSIONAHA.108.114298. PMC 2680209. PMID 18981330. Retrieved 2009-11-29. [2]
^ Petrou, I.; et al. (2009). "A breakthrough therapy for dentin hypersensitivity: how dental products containing 8% arginine and calcium carbonate work to deliver effective relief of sensitive teeth.". The Journal of Clinical Dentisry 20 (1): 23–31. PMID 19489189.
^ Takeshi Naito, Hiroshi Irie, Kazuko Tsujimoto, Keiko Ikeda, Tsutomu Arakawa, A. Hajime Koyama (April 2009). "Antiviral effect of arginine against herpes simplex virus type 1". International Journal of Molecular Medicine 23 (4): 495–499. doi:10.3892/ijmm_00000156. PMID 19288025. Retrieved 2010-10-18.
^ Medical College of Georgia. "Diabetes Makes It Hard For Blood Vessels To Relax." ScienceDaily 1 February 2008. 1 February 2008
^ Schulman SP, Becker LC, Kass DA, Champion HC, Terrin ML, Forman S, Ernst KV, Kelemen MD et al. (January 2006). "L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.". JAMA : the journal of the American Medical Association 295 (1): 58–64. doi:10.1001/jama.295.1.58. PMID 16391217.
^ This study has been discussed in some detail in : "Reverse Heart Disease Now" by Stephen T Sinatra MD and James C Roberts MD, publ. Wiley 2006 ISBN 0-471-74704-1 at pp 111-113.
^ Sapienza MA, Kharitonov SA, Horvath I, Chung KF, Barnes PJ. "Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects." Thorax. 1998 Mar;53(3):172-5.
^ Alba-Roth J, Müller O, Schopohl J, von Werder K (1988). "Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion". J Clin Endocrinol Metab 67 (6): 1186–9. doi:10.1210/jcem-67-6-1186. PMID 2903866.
^ U.S. National Library of Medicine (September 2009). Growth hormone stimulation test
^ Koga Y, Akita Y, Junko N, Yatsuga S, Povalko N, Fukiyama R, Ishii M, Matsuishi T (June 2006). "Endothelial dysfunction in MELAS improved by l-arginine supplementation". Neurology 66 (11): 1766–9. doi:10.1212/01.wnl.0000220197.36849.1e. PMID 16769961.
^ Koga Y (November 2008). "[L-arginine therapy on MELAS]" (in Japanese). Rinsho Shinkeigaku 48 (11): 1010–2. PMID 19198147.
^ Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Katayama K, Matsuishi T (2007). "MELAS and L-arginine therapy". Mitochondrion 7 (1–2): 133–9. doi:10.1016/j.mito.2006.11.006. PMID 17276739.
^ Finsterer J (November 2009). "Management of mitochondrial stroke-like-episodes". Eur. J. Neurol. 16 (11): 1178–84. doi:10.1111/j.1468-1331.2009.02789.x. PMID 19780807.
^ MORRIS SM (1995). ROLE OF ARGININE SYNTHESIS IN SURGICAL SEPSIS. Retrieved 2010-02-22.
^ Tissot-Favre A, Brette R (May–June 1970). "Therapeutic effects of arginine malate in alcoholic cirrhosis". Therapie 25 (3): 629–33. PMID 5431854.
^ Vadillo-Ortega F et al. (2011). "Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medical food on pre-eclampsia in high risk population: randomised controlled trial". British Medical Journal 342: d2901–d2901. doi:10.1136/bmj.d2901.
[edit]External links
Wikimedia Commons has media related to: arginine
NIST Chemistry Webbook
Mayo Clinic discussion of Arginine.
National Institute of Health discussion of Arginine.
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Thursday, October 6, 2011
Recently, the who, Medical Spa of Italy (in Italian Terme Terme ) spoke of the journey.
Japanese Tamagawa hot spring , etc. Unlike seem to be very bluntly how the curriculum is organized treatment.
So, be noted that, in the world medical tourism (also called health tourism.) Trends.
And medical tourism, package tours by a set of medical services and tourism, foreign travelers checkups, cosmetic surgery, corrective eye surgery and other medical services than the country of tourists, cheap and unique to that country, as well 療術 tradition, but an attempt to provide tourism.
India, Thailand, Greece, Panama, the Arab Federation, China, Philippines, Singapore, Bangladesh, Argentina, etc., have become popular. .
Particularly active in India, what's that thing also serves as therapy and yoga.
Here the Indian calendar medical therapy , but there is.
First ①, send a medical certificate before leaving India, subject to risk assessment.
So ②, should hold OK, coming a policy of surgery and treatment strategies.
So ③, finally, starting in India.
④ In India, subject to consulting a doctor.
Hospitalization ⑤, surgery.
Received postoperative measures ⑥, after the rest, returning home.
It seems like.
So what have any tour package.
Packages vary by country but, for example, a package of medical tourism to India's recruitment in America, there is something like the following.
○ joint replacement surgery
for knee replacement surgery, hip replacement surgery either at night seven days, and that it $ 12,000.
Cardiac surgery ○ - If heart surgery in the United States, but consuming three million dollars, went to medical tourism in India, if the surgery, live on eight thousand dollars.
Plastic Surgery ○ - the latest technology in surgery, receive in India.
Rates in breast implants, $ 4,500 (less any course of seven days stay), such as wrinkle firming facial, $ 5,000 in the nose, $ 4,500, belly fat removal surgery, $ 4,750 in liposuction, $ 6,000, seems like place.
Other ○, for the teeth, bleaching, implants, and other care, such as the menu bar, and some packages such as eye care.
In Japan, people go on a journey of medical tourism in Southeast Asia seems quite high.
In addition, the Korean drama "Winter Sonata" has been used to shoot the Korean National Cancer Center, and embark on Cancer attract popular Japanese drama that Ayakatsu etc., seems to have plans.
In Japan, Myoko , etc., seem to have a municipality that advocates medical tourism, in the heart and healing care springs, such as a modified human with surgery bluntly itself of these foreign, and dramatic, sham appears to have been.
When it comes to medical applications in Japan this rhythm, but the zones need to be.
In part, medical tourism initiative Fukui type , such as the movement is.
Nevertheless, medical tourism, "While traveling, my situation so far, may be increased at a lower price," it would have received its attractive scheme.
First time that this success, serious, ecotourism, I knew I would have lost it.
Reference sites
That readers of this blog (here)
... The «ground zero | Article List | U.S. new homes, ... »How China
2010-08-05 21:10:03
Medical Tourism is noteworthy in the world (India)
Subject: Information Society
2009.4.28 article ( updated again )
Hospital food is prepared according to international patients
The most advanced medical equipment
In New Delhi, India, low cost surgery, medical equipment and cutting-edge
Advanced medical technology with the doctor is listening
Now, going to India for fertility treatment in Japan, including living donor liver transplantation
There you can go to China to undergo a surgery, and Western Europe,
In between such people living in Africa, went to medical tourism in developing countries,
The gaining popularity of the surgery.
In the United States, arrhythmia surgery for women in their late 60s who lives in Las Vegas
But undergo, 5000 $ 170,000 (£ 17.5 million in Japanese yen) were required.
If you take the same level of surgery in India to 10000 dollars ($ 10,000) receive less.
Had been covering the hospital in New Delhi, India, are using the treatment of European countries.
In addition, hospitals are not prepared according to hospital food culture around the world, good hospitality,
If the diet and the enormous care, a delicious menu of great content.
For surgery, the doctor of Indian doctors and patients, because it always takes a communicate
Patients can be safe. In addition, technologies such as medical doctor at the same level as the United States.
Use the same cutting-edge medical equipment, such as the United States, trained and specialized doctor
Because the staff, the level of medical technology in India is considerably higher and has attracted worldwide attention.
Hospitals and medical tourism, say that you support the patient and how health care planners
Support that have been borrowed.
Also ensure that proper rest house. Restaurants, coffee shops, cafes and book well
To be able to access in the lobby of the hospital in its entirety.
Also, if people come with me to medical tourism for 24 hours concierge, shopping and sightseeing
For any stay in India until, the person who looked after.
Why say how well the service can receive health care cheap enough, the
Low prices for India, about one-tenth of the salary of doctors and Europe than in Western countries.
Thus, in India for people in developed countries, receive less advanced medical care. But
The people living in India to become expensive care, not take it hard.
Risks of medical tourism is in some way, and postoperative care issues,
For developing countries, and there is no risk of infection and water for say,
Challenge to develop a health care that many have been left.
Also by country, such as legal rights, and always will be all well.
In Japan, some asking for donations that go hundreds of millions when performing surgery in the United States.
If India
Japanese Tamagawa hot spring , etc. Unlike seem to be very bluntly how the curriculum is organized treatment.
So, be noted that, in the world medical tourism (also called health tourism.) Trends.
And medical tourism, package tours by a set of medical services and tourism, foreign travelers checkups, cosmetic surgery, corrective eye surgery and other medical services than the country of tourists, cheap and unique to that country, as well 療術 tradition, but an attempt to provide tourism.
India, Thailand, Greece, Panama, the Arab Federation, China, Philippines, Singapore, Bangladesh, Argentina, etc., have become popular. .
Particularly active in India, what's that thing also serves as therapy and yoga.
Here the Indian calendar medical therapy , but there is.
First ①, send a medical certificate before leaving India, subject to risk assessment.
So ②, should hold OK, coming a policy of surgery and treatment strategies.
So ③, finally, starting in India.
④ In India, subject to consulting a doctor.
Hospitalization ⑤, surgery.
Received postoperative measures ⑥, after the rest, returning home.
It seems like.
So what have any tour package.
Packages vary by country but, for example, a package of medical tourism to India's recruitment in America, there is something like the following.
○ joint replacement surgery
for knee replacement surgery, hip replacement surgery either at night seven days, and that it $ 12,000.
Cardiac surgery ○ - If heart surgery in the United States, but consuming three million dollars, went to medical tourism in India, if the surgery, live on eight thousand dollars.
Plastic Surgery ○ - the latest technology in surgery, receive in India.
Rates in breast implants, $ 4,500 (less any course of seven days stay), such as wrinkle firming facial, $ 5,000 in the nose, $ 4,500, belly fat removal surgery, $ 4,750 in liposuction, $ 6,000, seems like place.
Other ○, for the teeth, bleaching, implants, and other care, such as the menu bar, and some packages such as eye care.
In Japan, people go on a journey of medical tourism in Southeast Asia seems quite high.
In addition, the Korean drama "Winter Sonata" has been used to shoot the Korean National Cancer Center, and embark on Cancer attract popular Japanese drama that Ayakatsu etc., seems to have plans.
In Japan, Myoko , etc., seem to have a municipality that advocates medical tourism, in the heart and healing care springs, such as a modified human with surgery bluntly itself of these foreign, and dramatic, sham appears to have been.
When it comes to medical applications in Japan this rhythm, but the zones need to be.
In part, medical tourism initiative Fukui type , such as the movement is.
Nevertheless, medical tourism, "While traveling, my situation so far, may be increased at a lower price," it would have received its attractive scheme.
First time that this success, serious, ecotourism, I knew I would have lost it.
Reference sites
That readers of this blog (here)
... The «ground zero | Article List | U.S. new homes, ... »How China
2010-08-05 21:10:03
Medical Tourism is noteworthy in the world (India)
Subject: Information Society
2009.4.28 article ( updated again )
Hospital food is prepared according to international patients
The most advanced medical equipment
In New Delhi, India, low cost surgery, medical equipment and cutting-edge
Advanced medical technology with the doctor is listening
Now, going to India for fertility treatment in Japan, including living donor liver transplantation
There you can go to China to undergo a surgery, and Western Europe,
In between such people living in Africa, went to medical tourism in developing countries,
The gaining popularity of the surgery.
In the United States, arrhythmia surgery for women in their late 60s who lives in Las Vegas
But undergo, 5000 $ 170,000 (£ 17.5 million in Japanese yen) were required.
If you take the same level of surgery in India to 10000 dollars ($ 10,000) receive less.
Had been covering the hospital in New Delhi, India, are using the treatment of European countries.
In addition, hospitals are not prepared according to hospital food culture around the world, good hospitality,
If the diet and the enormous care, a delicious menu of great content.
For surgery, the doctor of Indian doctors and patients, because it always takes a communicate
Patients can be safe. In addition, technologies such as medical doctor at the same level as the United States.
Use the same cutting-edge medical equipment, such as the United States, trained and specialized doctor
Because the staff, the level of medical technology in India is considerably higher and has attracted worldwide attention.
Hospitals and medical tourism, say that you support the patient and how health care planners
Support that have been borrowed.
Also ensure that proper rest house. Restaurants, coffee shops, cafes and book well
To be able to access in the lobby of the hospital in its entirety.
Also, if people come with me to medical tourism for 24 hours concierge, shopping and sightseeing
For any stay in India until, the person who looked after.
Why say how well the service can receive health care cheap enough, the
Low prices for India, about one-tenth of the salary of doctors and Europe than in Western countries.
Thus, in India for people in developed countries, receive less advanced medical care. But
The people living in India to become expensive care, not take it hard.
Risks of medical tourism is in some way, and postoperative care issues,
For developing countries, and there is no risk of infection and water for say,
Challenge to develop a health care that many have been left.
Also by country, such as legal rights, and always will be all well.
In Japan, some asking for donations that go hundreds of millions when performing surgery in the United States.
If India
Tuesday, October 4, 2011
STAYING HEALTHY, FOR MOST OF US, FOLLOWS THE SAME BASIC STRATEGY — moderation, moderation, moderation. Still, it’s no guarantee that something won’t afflict you sooner or later. When you get sick, it can wreak havoc financially and otherwise, and having a support system becomes critical. While researchers try their hardest to cure ailments (for the greater good or personal gain), it is up to us to be smart patients, and demand for what’s best for us.
Featured PostsSTAYING HEALTHY, FOR MOST OF US, FOLLOWS THE SAME BASIC STRATEGY — moderation, moderation, moderation. Still, it’s no guarantee that something won’t afflict you sooner or later. When you get sick, it can wreak havoc financially and otherwise, and having a support system becomes critical. While researchers try their hardest to cure ailments (for the greater good or personal gain), it is up to us to be smart patients, and demand for what’s best for us.
Featured Posts
More from this author
Road Biking Colorado National Monument
SheSpoke. Living her adult childhood
+12 more images
After a decade and a half of strictly mountain biking, I’ve made the transition over to the dark side. A friend of mine lent me her neon yellow Trek from the 1980s, and I’ve been commuting and playing around the urban trails of Denver for a few months now, excited at how light and fast it is. I’ve been a spectating fan of road biking since the early days of Lance, marveling at how anyone can pedal for six hours up and over mountains for well over 100 miles. I’m now starting to get it. Independence Monument, a beautiful product of erosion, in the background These bikes are light, and the pedaling is continuous uphill and you’re coasting downhill. In fact, on the downhill all you’re really worried about is running over a frightened rodent who will then send you flying through the air like the Greatest American Hero(ine). When I started riding 30+ miles on the road bike, (akin to riding 10+ intermediate miles on the mountain bike), I was looking for pai
More from this author
Quiet time on the running trail
Minnesota Transplant
“The gun goes off and everything changes … the world changes … and nothing else really matters.” ~ Patti Sue Plumer, American long-distance runner Running is an effective weight-management tool, and it smooths the rough edges on my stress profile, too. I know for a fact I am bitchier on days I don’t get exercise. When I need quiet time, I put on my Asics and dash out the door. I often run with my iPod, but when I’m in a pickle, I leave it behind and just pound the pavement while I think about my breathing. I distinctly remember a 6-mile run on a summer day five years ago. The day before, I had to lay off two staff members, and it felt like choosing which toes I wanted to have removed. I have no doubt that black day was more awful for the two women I laid off, and I don’t mean to minimize their experiences as I lament my role in middle-management. But (yes, but!) unless you’re Cruella DeVille, telling people you’ve hired and mentored
The Latest Posts in Health Recently posted on WordPress.com Subscribe
Watch the Fine Print When You’re Watching Your Weight
joycemcdonald
It’s okay to go off your diet once in awhile. We all do it now and then. Just be careful not to do it every day or so. Maybe once a week is good for you. The problem may not be how often we fudge a little, but what it is we choose when we cheat. You can stop by Starbucks for a cup of coffee or you can have Starbucks Venti (20 oz.) White chocolate Mocha with 2% milk and whipped cream. If you give in to the Venti, you will be taking on more calories than if you had a McDonald’s Quarter Pounder with Cheese! You would be adding 580 calories and 15 grams of saturated fat. Of course you could have the Venti with non-fat milk and no whipped cream. That would be 130 calories less. Maybe you like Marie Callender’s Chicken Pot Pie. The 16.5 oz. package proudly says “only 520″ calories. If you read carefully that is for only half a pie! Eat the whole thing and you will have consumed 1,040 calories, more than a day’s worth of saturated fat, and an e
Scary, sick voice!!!
My Blogging Path
On Tuesday, October 4, 2011 at 10:38 AM, I received an “Auto-Forwarded voicemail message from (xxx) xxx-xxxx”. And the email showed a “Transcribed Message” that was rated “Good” by me because they didn’t spell my name correctly, one word was incorrect and the rest drifted to incoherence. This is partially because the caller didn’t sound the same! His voice is steady, deeper and scary! It’s sounds congested as if he has a very bad cold in the sinuses. The pattern of his speech and word usage sounded like him. But I have a weird feeling it is NOT his usual “self”. OMG! What’s going on? Is he still really alive? What are you people pulling over my ear holes? Perhaps, he needs your boost/prayer because he has “special gifts”, which I senses/knew/test that we last saw each other in person. Again, his professionalism will be noted (in my “Akashic Book/s of Life”) for returning a long-distant phone
MMR Yet Again
Letting Off Steam
The Daily Mail will not let go of the mythical MMR-autism link. Their writer Sally Beck claims that:- New American research shows that there could be a link between the controversial MMR triple vaccine and autism and bowel disease in children. This is complete bollocks, to use a technical term. First it is not new research. The Times reported it back in 2006. It is instructive to compare the two articles. The Times wrote: The latest study, led by Arthur Krigsman, of New York University School of Medicine, involved 275 children. Serious intestinal inflammations were found in some of the autistic children and biopsies of gut tissue were performed on 82 of them. Of these, 70 are said to have shown evidence of the measles virus, which so far has been confirmed in 14 cases by more stringent DNA tests. Steve Walker, assistant professor at Wake Forest University Medical Centre, North Carolina, who analysed the gut samples, said the work mirrored Dr Wakefield’s study. All the children involved
+4 more images
OBSTACLE COURSE
snowbirdredux
Ice Surfer, Lake Michigan
Great Pictures Collection
Taking a look at eye safety – Part 1
Touching Base
Laura Mercier Tinted Moisturizer
fnkyluda
Better Mood with Singing
+10 more images
Break for Intestines
Green Plate Dinners
Just Live With It: Losing The American Dream
Fidlerten Place
Whatever your political beliefs are, I would ask that you set those aside, if but for a short while. I ask that because I would like to take a moment to talk about the American Dream, which is something I believe that everyone can relate to. Of course, there are as many perceptions of what the American Dream is as there are people dreaming of it. Regardless of how those dreams are realized, I think that at the most basic level, most people seek to have a sense of prosperity, security and well-being. Each generation seeks to be just a bit better off than the one before, and hopes that their children will be just a bit better off still. As far as the American Dream goes, I know that I am very fortunate. Some might even say “blessed”, though that would not be my personal choice of words. I’ve worked hard and graduated college. I have a good job and even own my own home. I am not by any measure “wealthy”. I don’t keep up with the Joneses. But, I certainly do better than my fathe
Eating with Autism-1
Accidental Autism
One of my favorite measures of “well-being” is eating and appetite; when we are happy and contented, most of us enjoy eating and sharing meals with friends and family. When anxiety and depression set in, this simple and universal pleasure is lost to us. A recent piece in the New York Times shows families of all types eating together and enjoying the “feeling that everything is going to be all right, if only for the moment”. The photos are by Stephanie Sinclair and text by Sam Sifton. Our family, like many these days, does not gather together often enough because of international travel for work and the life styles of our extended families. We did recently have my husband and his three siblings gathered in our house and our daughter who has severe autism was able to join us. We had been warned by her staff at her group home that she had been unstable and dangerous after a recent medication change. They advised us not to bring her home for this gathering. What
Housing Priorities for Retiring Baby Boomers – Lifestyle and Health Related Issues Are Most Important
John Murphy Reports
Now that America has exhausted the first time home buyer with the various tax credits, it’s time we switch back to the real movers and shakers in housing – that of course is the massive generation known as the baby boomers. They are starting to retire at a rapid clip and their choices with regard to housing will have a major impact on markets across the U.S. Builder Magazine recently published an interesting article that highlighted some of the results from a baby boomer poll conducted by NPR, The Robert Johnson Foundation and the Harvard School of Public Health, the results of which may be found here. What’s great about the survey is that they break it in to two groups – those who have already retired and those who are still pre-retirement. In many of the questions there is a distinct difference between the two groups. There were notable differences of opinions with regard to good public schools, public transportation, or the ability participate in voluntee
CST#1
FitDre : Mobility.Athletics.Strength (MAS) by Andre Vazquez
If you’re approaching 30 or are already in your 30′s (like me) then you already know you GOTTA train your biggest and baddest muscle of all, YOUR HEART! Push and keep that thing ticking more effectively and efficiently when you most need it. Cardio Strength Training (CST) #1 uses the following template which can later be switched and swapped out for other exercises. It borrows from the book Cardio Strength Training by Robert Dos Remedios (plug). It’s one of my favorite templates to borrow. For this workout everything is 10 reps (change your reps according to your need/goals). You will run through the entire series about 5x in under an hour to burn anywhere from 500-800 calories. [Explode] Single Leg Power Step-Up Jump [Major Hip/Knee] OHP, Step-Up, Rev.Lunge [Push/Chest] Prone MB Passes [Pull/Back] LB Rows [All Core] SB Tucks/Pikes Abs: Bikes Scissors Side Plank Ups -Andre Vazquez MAS:FitDre Mobility.Athletics.Strength @FitDre www.fitdre.wordpress.com Become a LIKE
Switchout, 27 May 2011, Fighting Through the Blahs
Switchout Circuit Training
Switchout Circuit Training Arms (3) Triceps – press, dips, kickbacks Legs (3) quads, hams, squats Chest (3) center, lower, upper Shoulders (3) straight, straight, upper flat bench + eagle flies 1×15@bar // 1×10@95 // 2×10@115 + 2×10@5 // 2×10@10 T-handle + tricep press 3×10@45 + 3×10@35 quads + shoulder press 3×10@50 3×10@20 db dips 3×10 hams + kickbacks 3×10@45 + 2×10@15 // 1×10@20 DB incline bench + DB squats 3×10@20 + 3×10@20 Explanation :: The concept behind this exercise strategy is simple; while you are working one body part, the other is resting. There is no rest period between sets. By switching between exercises quickly, your heart rate remains high. This burns calo
One Day at a Time…
The Incredible Shrinking Lady
So yesterday I ran into an old friend of mine, and we went to dinner with our significant others. This was my first time at a restaurant since I started my diet two weeks ago. Background history: before the diet started, I was going out to dinner most nights of the week somewhere, so this diet has significantly reduced my outgoing money on food. (yay!) At the restaurant we had great conversations, and I had my challenges with wanting to eat some of the homemade, honey cornbread that came out on a griddle, but I still made it. Wow! I made it through the whole dinner without taking a bite of anything else. At this moment I am so happy that I had the will-power to do it. At the time last night I was ready to break the diet to have some ‘pownbread. Hindsight is 20/20. Tonight is the end of my 2nd week’s weigh in, and I’m really looking forward to it. Mathematically speaking, I should have lost about 4 lbs this past week with the amount of calories consumed, burnt and expe
A Hard to Swallow Subject
Hollani's Hot Topics
This weekend while cooking for several of my co-workers, I found myself praying, “Please Lord, don’t let this food make them sick!” If you’re like me, your are extremely paranoid with all of these recent food related illnesses. Cantaloupe – Listeria Ground Beef – E. coli (Ground Turkey earlier this year) Lettuce – Listeria Spinach Dip – Listeria Turkey Burgers – Salmonella Strawberries – E. coli Papaya – Salmonella Eggs (2010) – Salmonella It’s really quite scary when you think about it. Especially since I eat all of the foods I listed above. I’m especially bad at eating things with raw eggs in it (cookie dough, brownie batter – yea, I still sneak it a spoonful every now and then). I think about the families who’ve lost someone from one of these tainted products. How devastating is that? “My brother died because he ate cantaloupe for breakfast.” Is this the new norm? Washing food
Prevent breast cancer, with exercise.
Exercise doesn’t just lower the number on the scale, studies now show that it can also reduce breast cancer risk. Click here for more Information.
ACO Roadblocks, Courtesy of CMS
Uncommon Clarity
We recently reviewed an article outlining the current debate between the American Telemedicine Association (ATA) and Centers for Medicare & Medicaid Services (CMS) regarding the statutory restrictions placed on telehealth by CMS in certain rules effecting accountable care organizations (ACOs). In summary, ATA is asking that five Medicare requirements that effectively limit the use of telemedicine—by prohibiting reimbursement—be waived or modified. It is ironic that CMS is supporting unnecessary road blocks to ACO enablement, a care delivery methodology that is a cornerstone of the 2009 health reform legislation. At the core of the government’s support for ACOs is the idea that Medicare and Medicaid spending is unsustainable and a system that rewards providers for delivering the same (or better care) could be most impactful by better managing patients with chronic conditions, reducing readmissions and minimizing ER visits. Thus, it seems counterintuitive that new approaches to d
More from this author
Road Biking Colorado National Monument
SheSpoke. Living her adult childhood
+12 more images
After a decade and a half of strictly mountain biking, I’ve made the transition over to the dark side. A friend of mine lent me her neon yellow Trek from the 1980s, and I’ve been commuting and playing around the urban trails of Denver for a few months now, excited at how light and fast it is. I’ve been a spectating fan of road biking since the early days of Lance, marveling at how anyone can pedal for six hours up and over mountains for well over 100 miles. I’m now starting to get it. Independence Monument, a beautiful product of erosion, in the background These bikes are light, and the pedaling is continuous uphill and you’re coasting downhill. In fact, on the downhill all you’re really worried about is running over a frightened rodent who will then send you flying through the air like the Greatest American Hero(ine). When I started riding 30+ miles on the road bike, (akin to riding 10+ intermediate miles on the mountain bike), I was looking for pai
More from this author
Quiet time on the running trail
Minnesota Transplant
“The gun goes off and everything changes … the world changes … and nothing else really matters.” ~ Patti Sue Plumer, American long-distance runner Running is an effective weight-management tool, and it smooths the rough edges on my stress profile, too. I know for a fact I am bitchier on days I don’t get exercise. When I need quiet time, I put on my Asics and dash out the door. I often run with my iPod, but when I’m in a pickle, I leave it behind and just pound the pavement while I think about my breathing. I distinctly remember a 6-mile run on a summer day five years ago. The day before, I had to lay off two staff members, and it felt like choosing which toes I wanted to have removed. I have no doubt that black day was more awful for the two women I laid off, and I don’t mean to minimize their experiences as I lament my role in middle-management. But (yes, but!) unless you’re Cruella DeVille, telling people you’ve hired and mentored
The Latest Posts in Health Recently posted on WordPress.com Subscribe
Watch the Fine Print When You’re Watching Your Weight
joycemcdonald
It’s okay to go off your diet once in awhile. We all do it now and then. Just be careful not to do it every day or so. Maybe once a week is good for you. The problem may not be how often we fudge a little, but what it is we choose when we cheat. You can stop by Starbucks for a cup of coffee or you can have Starbucks Venti (20 oz.) White chocolate Mocha with 2% milk and whipped cream. If you give in to the Venti, you will be taking on more calories than if you had a McDonald’s Quarter Pounder with Cheese! You would be adding 580 calories and 15 grams of saturated fat. Of course you could have the Venti with non-fat milk and no whipped cream. That would be 130 calories less. Maybe you like Marie Callender’s Chicken Pot Pie. The 16.5 oz. package proudly says “only 520″ calories. If you read carefully that is for only half a pie! Eat the whole thing and you will have consumed 1,040 calories, more than a day’s worth of saturated fat, and an e
Scary, sick voice!!!
My Blogging Path
On Tuesday, October 4, 2011 at 10:38 AM, I received an “Auto-Forwarded voicemail message from (xxx) xxx-xxxx”. And the email showed a “Transcribed Message” that was rated “Good” by me because they didn’t spell my name correctly, one word was incorrect and the rest drifted to incoherence. This is partially because the caller didn’t sound the same! His voice is steady, deeper and scary! It’s sounds congested as if he has a very bad cold in the sinuses. The pattern of his speech and word usage sounded like him. But I have a weird feeling it is NOT his usual “self”. OMG! What’s going on? Is he still really alive? What are you people pulling over my ear holes? Perhaps, he needs your boost/prayer because he has “special gifts”, which I senses/knew/test that we last saw each other in person. Again, his professionalism will be noted (in my “Akashic Book/s of Life”) for returning a long-distant phone
MMR Yet Again
Letting Off Steam
The Daily Mail will not let go of the mythical MMR-autism link. Their writer Sally Beck claims that:- New American research shows that there could be a link between the controversial MMR triple vaccine and autism and bowel disease in children. This is complete bollocks, to use a technical term. First it is not new research. The Times reported it back in 2006. It is instructive to compare the two articles. The Times wrote: The latest study, led by Arthur Krigsman, of New York University School of Medicine, involved 275 children. Serious intestinal inflammations were found in some of the autistic children and biopsies of gut tissue were performed on 82 of them. Of these, 70 are said to have shown evidence of the measles virus, which so far has been confirmed in 14 cases by more stringent DNA tests. Steve Walker, assistant professor at Wake Forest University Medical Centre, North Carolina, who analysed the gut samples, said the work mirrored Dr Wakefield’s study. All the children involved
+4 more images
OBSTACLE COURSE
snowbirdredux
Ice Surfer, Lake Michigan
Great Pictures Collection
Taking a look at eye safety – Part 1
Touching Base
Laura Mercier Tinted Moisturizer
fnkyluda
Better Mood with Singing
+10 more images
Break for Intestines
Green Plate Dinners
Just Live With It: Losing The American Dream
Fidlerten Place
Whatever your political beliefs are, I would ask that you set those aside, if but for a short while. I ask that because I would like to take a moment to talk about the American Dream, which is something I believe that everyone can relate to. Of course, there are as many perceptions of what the American Dream is as there are people dreaming of it. Regardless of how those dreams are realized, I think that at the most basic level, most people seek to have a sense of prosperity, security and well-being. Each generation seeks to be just a bit better off than the one before, and hopes that their children will be just a bit better off still. As far as the American Dream goes, I know that I am very fortunate. Some might even say “blessed”, though that would not be my personal choice of words. I’ve worked hard and graduated college. I have a good job and even own my own home. I am not by any measure “wealthy”. I don’t keep up with the Joneses. But, I certainly do better than my fathe
Eating with Autism-1
Accidental Autism
One of my favorite measures of “well-being” is eating and appetite; when we are happy and contented, most of us enjoy eating and sharing meals with friends and family. When anxiety and depression set in, this simple and universal pleasure is lost to us. A recent piece in the New York Times shows families of all types eating together and enjoying the “feeling that everything is going to be all right, if only for the moment”. The photos are by Stephanie Sinclair and text by Sam Sifton. Our family, like many these days, does not gather together often enough because of international travel for work and the life styles of our extended families. We did recently have my husband and his three siblings gathered in our house and our daughter who has severe autism was able to join us. We had been warned by her staff at her group home that she had been unstable and dangerous after a recent medication change. They advised us not to bring her home for this gathering. What
Housing Priorities for Retiring Baby Boomers – Lifestyle and Health Related Issues Are Most Important
John Murphy Reports
Now that America has exhausted the first time home buyer with the various tax credits, it’s time we switch back to the real movers and shakers in housing – that of course is the massive generation known as the baby boomers. They are starting to retire at a rapid clip and their choices with regard to housing will have a major impact on markets across the U.S. Builder Magazine recently published an interesting article that highlighted some of the results from a baby boomer poll conducted by NPR, The Robert Johnson Foundation and the Harvard School of Public Health, the results of which may be found here. What’s great about the survey is that they break it in to two groups – those who have already retired and those who are still pre-retirement. In many of the questions there is a distinct difference between the two groups. There were notable differences of opinions with regard to good public schools, public transportation, or the ability participate in voluntee
CST#1
FitDre : Mobility.Athletics.Strength (MAS) by Andre Vazquez
If you’re approaching 30 or are already in your 30′s (like me) then you already know you GOTTA train your biggest and baddest muscle of all, YOUR HEART! Push and keep that thing ticking more effectively and efficiently when you most need it. Cardio Strength Training (CST) #1 uses the following template which can later be switched and swapped out for other exercises. It borrows from the book Cardio Strength Training by Robert Dos Remedios (plug). It’s one of my favorite templates to borrow. For this workout everything is 10 reps (change your reps according to your need/goals). You will run through the entire series about 5x in under an hour to burn anywhere from 500-800 calories. [Explode] Single Leg Power Step-Up Jump [Major Hip/Knee] OHP, Step-Up, Rev.Lunge [Push/Chest] Prone MB Passes [Pull/Back] LB Rows [All Core] SB Tucks/Pikes Abs: Bikes Scissors Side Plank Ups -Andre Vazquez MAS:FitDre Mobility.Athletics.Strength @FitDre www.fitdre.wordpress.com Become a LIKE
Switchout, 27 May 2011, Fighting Through the Blahs
Switchout Circuit Training
Switchout Circuit Training Arms (3) Triceps – press, dips, kickbacks Legs (3) quads, hams, squats Chest (3) center, lower, upper Shoulders (3) straight, straight, upper flat bench + eagle flies 1×15@bar // 1×10@95 // 2×10@115 + 2×10@5 // 2×10@10 T-handle + tricep press 3×10@45 + 3×10@35 quads + shoulder press 3×10@50 3×10@20 db dips 3×10 hams + kickbacks 3×10@45 + 2×10@15 // 1×10@20 DB incline bench + DB squats 3×10@20 + 3×10@20 Explanation :: The concept behind this exercise strategy is simple; while you are working one body part, the other is resting. There is no rest period between sets. By switching between exercises quickly, your heart rate remains high. This burns calo
One Day at a Time…
The Incredible Shrinking Lady
So yesterday I ran into an old friend of mine, and we went to dinner with our significant others. This was my first time at a restaurant since I started my diet two weeks ago. Background history: before the diet started, I was going out to dinner most nights of the week somewhere, so this diet has significantly reduced my outgoing money on food. (yay!) At the restaurant we had great conversations, and I had my challenges with wanting to eat some of the homemade, honey cornbread that came out on a griddle, but I still made it. Wow! I made it through the whole dinner without taking a bite of anything else. At this moment I am so happy that I had the will-power to do it. At the time last night I was ready to break the diet to have some ‘pownbread. Hindsight is 20/20. Tonight is the end of my 2nd week’s weigh in, and I’m really looking forward to it. Mathematically speaking, I should have lost about 4 lbs this past week with the amount of calories consumed, burnt and expe
A Hard to Swallow Subject
Hollani's Hot Topics
This weekend while cooking for several of my co-workers, I found myself praying, “Please Lord, don’t let this food make them sick!” If you’re like me, your are extremely paranoid with all of these recent food related illnesses. Cantaloupe – Listeria Ground Beef – E. coli (Ground Turkey earlier this year) Lettuce – Listeria Spinach Dip – Listeria Turkey Burgers – Salmonella Strawberries – E. coli Papaya – Salmonella Eggs (2010) – Salmonella It’s really quite scary when you think about it. Especially since I eat all of the foods I listed above. I’m especially bad at eating things with raw eggs in it (cookie dough, brownie batter – yea, I still sneak it a spoonful every now and then). I think about the families who’ve lost someone from one of these tainted products. How devastating is that? “My brother died because he ate cantaloupe for breakfast.” Is this the new norm? Washing food
Prevent breast cancer, with exercise.
Exercise doesn’t just lower the number on the scale, studies now show that it can also reduce breast cancer risk. Click here for more Information.
ACO Roadblocks, Courtesy of CMS
Uncommon Clarity
We recently reviewed an article outlining the current debate between the American Telemedicine Association (ATA) and Centers for Medicare & Medicaid Services (CMS) regarding the statutory restrictions placed on telehealth by CMS in certain rules effecting accountable care organizations (ACOs). In summary, ATA is asking that five Medicare requirements that effectively limit the use of telemedicine—by prohibiting reimbursement—be waived or modified. It is ironic that CMS is supporting unnecessary road blocks to ACO enablement, a care delivery methodology that is a cornerstone of the 2009 health reform legislation. At the core of the government’s support for ACOs is the idea that Medicare and Medicaid spending is unsustainable and a system that rewards providers for delivering the same (or better care) could be most impactful by better managing patients with chronic conditions, reducing readmissions and minimizing ER visits. Thus, it seems counterintuitive that new approaches to d
Featured PostsSTAYING HEALTHY, FOR MOST OF US, FOLLOWS THE SAME BASIC STRATEGY — moderation, moderation, moderation. Still, it’s no guarantee that something won’t afflict you sooner or later. When you get sick, it can wreak havoc financially and otherwise, and having a support system becomes critical. While researchers try their hardest to cure ailments (for the greater good or personal gain), it is up to us to be smart patients, and demand for what’s best for us.
Featured Posts
More from this author
Road Biking Colorado National Monument
SheSpoke. Living her adult childhood
+12 more images
After a decade and a half of strictly mountain biking, I’ve made the transition over to the dark side. A friend of mine lent me her neon yellow Trek from the 1980s, and I’ve been commuting and playing around the urban trails of Denver for a few months now, excited at how light and fast it is. I’ve been a spectating fan of road biking since the early days of Lance, marveling at how anyone can pedal for six hours up and over mountains for well over 100 miles. I’m now starting to get it. Independence Monument, a beautiful product of erosion, in the background These bikes are light, and the pedaling is continuous uphill and you’re coasting downhill. In fact, on the downhill all you’re really worried about is running over a frightened rodent who will then send you flying through the air like the Greatest American Hero(ine). When I started riding 30+ miles on the road bike, (akin to riding 10+ intermediate miles on the mountain bike), I was looking for pai
More from this author
Quiet time on the running trail
Minnesota Transplant
“The gun goes off and everything changes … the world changes … and nothing else really matters.” ~ Patti Sue Plumer, American long-distance runner Running is an effective weight-management tool, and it smooths the rough edges on my stress profile, too. I know for a fact I am bitchier on days I don’t get exercise. When I need quiet time, I put on my Asics and dash out the door. I often run with my iPod, but when I’m in a pickle, I leave it behind and just pound the pavement while I think about my breathing. I distinctly remember a 6-mile run on a summer day five years ago. The day before, I had to lay off two staff members, and it felt like choosing which toes I wanted to have removed. I have no doubt that black day was more awful for the two women I laid off, and I don’t mean to minimize their experiences as I lament my role in middle-management. But (yes, but!) unless you’re Cruella DeVille, telling people you’ve hired and mentored
The Latest Posts in Health Recently posted on WordPress.com Subscribe
Watch the Fine Print When You’re Watching Your Weight
joycemcdonald
It’s okay to go off your diet once in awhile. We all do it now and then. Just be careful not to do it every day or so. Maybe once a week is good for you. The problem may not be how often we fudge a little, but what it is we choose when we cheat. You can stop by Starbucks for a cup of coffee or you can have Starbucks Venti (20 oz.) White chocolate Mocha with 2% milk and whipped cream. If you give in to the Venti, you will be taking on more calories than if you had a McDonald’s Quarter Pounder with Cheese! You would be adding 580 calories and 15 grams of saturated fat. Of course you could have the Venti with non-fat milk and no whipped cream. That would be 130 calories less. Maybe you like Marie Callender’s Chicken Pot Pie. The 16.5 oz. package proudly says “only 520″ calories. If you read carefully that is for only half a pie! Eat the whole thing and you will have consumed 1,040 calories, more than a day’s worth of saturated fat, and an e
Scary, sick voice!!!
My Blogging Path
On Tuesday, October 4, 2011 at 10:38 AM, I received an “Auto-Forwarded voicemail message from (xxx) xxx-xxxx”. And the email showed a “Transcribed Message” that was rated “Good” by me because they didn’t spell my name correctly, one word was incorrect and the rest drifted to incoherence. This is partially because the caller didn’t sound the same! His voice is steady, deeper and scary! It’s sounds congested as if he has a very bad cold in the sinuses. The pattern of his speech and word usage sounded like him. But I have a weird feeling it is NOT his usual “self”. OMG! What’s going on? Is he still really alive? What are you people pulling over my ear holes? Perhaps, he needs your boost/prayer because he has “special gifts”, which I senses/knew/test that we last saw each other in person. Again, his professionalism will be noted (in my “Akashic Book/s of Life”) for returning a long-distant phone
MMR Yet Again
Letting Off Steam
The Daily Mail will not let go of the mythical MMR-autism link. Their writer Sally Beck claims that:- New American research shows that there could be a link between the controversial MMR triple vaccine and autism and bowel disease in children. This is complete bollocks, to use a technical term. First it is not new research. The Times reported it back in 2006. It is instructive to compare the two articles. The Times wrote: The latest study, led by Arthur Krigsman, of New York University School of Medicine, involved 275 children. Serious intestinal inflammations were found in some of the autistic children and biopsies of gut tissue were performed on 82 of them. Of these, 70 are said to have shown evidence of the measles virus, which so far has been confirmed in 14 cases by more stringent DNA tests. Steve Walker, assistant professor at Wake Forest University Medical Centre, North Carolina, who analysed the gut samples, said the work mirrored Dr Wakefield’s study. All the children involved
+4 more images
OBSTACLE COURSE
snowbirdredux
Ice Surfer, Lake Michigan
Great Pictures Collection
Taking a look at eye safety – Part 1
Touching Base
Laura Mercier Tinted Moisturizer
fnkyluda
Better Mood with Singing
+10 more images
Break for Intestines
Green Plate Dinners
Just Live With It: Losing The American Dream
Fidlerten Place
Whatever your political beliefs are, I would ask that you set those aside, if but for a short while. I ask that because I would like to take a moment to talk about the American Dream, which is something I believe that everyone can relate to. Of course, there are as many perceptions of what the American Dream is as there are people dreaming of it. Regardless of how those dreams are realized, I think that at the most basic level, most people seek to have a sense of prosperity, security and well-being. Each generation seeks to be just a bit better off than the one before, and hopes that their children will be just a bit better off still. As far as the American Dream goes, I know that I am very fortunate. Some might even say “blessed”, though that would not be my personal choice of words. I’ve worked hard and graduated college. I have a good job and even own my own home. I am not by any measure “wealthy”. I don’t keep up with the Joneses. But, I certainly do better than my fathe
Eating with Autism-1
Accidental Autism
One of my favorite measures of “well-being” is eating and appetite; when we are happy and contented, most of us enjoy eating and sharing meals with friends and family. When anxiety and depression set in, this simple and universal pleasure is lost to us. A recent piece in the New York Times shows families of all types eating together and enjoying the “feeling that everything is going to be all right, if only for the moment”. The photos are by Stephanie Sinclair and text by Sam Sifton. Our family, like many these days, does not gather together often enough because of international travel for work and the life styles of our extended families. We did recently have my husband and his three siblings gathered in our house and our daughter who has severe autism was able to join us. We had been warned by her staff at her group home that she had been unstable and dangerous after a recent medication change. They advised us not to bring her home for this gathering. What
Housing Priorities for Retiring Baby Boomers – Lifestyle and Health Related Issues Are Most Important
John Murphy Reports
Now that America has exhausted the first time home buyer with the various tax credits, it’s time we switch back to the real movers and shakers in housing – that of course is the massive generation known as the baby boomers. They are starting to retire at a rapid clip and their choices with regard to housing will have a major impact on markets across the U.S. Builder Magazine recently published an interesting article that highlighted some of the results from a baby boomer poll conducted by NPR, The Robert Johnson Foundation and the Harvard School of Public Health, the results of which may be found here. What’s great about the survey is that they break it in to two groups – those who have already retired and those who are still pre-retirement. In many of the questions there is a distinct difference between the two groups. There were notable differences of opinions with regard to good public schools, public transportation, or the ability participate in voluntee
CST#1
FitDre : Mobility.Athletics.Strength (MAS) by Andre Vazquez
If you’re approaching 30 or are already in your 30′s (like me) then you already know you GOTTA train your biggest and baddest muscle of all, YOUR HEART! Push and keep that thing ticking more effectively and efficiently when you most need it. Cardio Strength Training (CST) #1 uses the following template which can later be switched and swapped out for other exercises. It borrows from the book Cardio Strength Training by Robert Dos Remedios (plug). It’s one of my favorite templates to borrow. For this workout everything is 10 reps (change your reps according to your need/goals). You will run through the entire series about 5x in under an hour to burn anywhere from 500-800 calories. [Explode] Single Leg Power Step-Up Jump [Major Hip/Knee] OHP, Step-Up, Rev.Lunge [Push/Chest] Prone MB Passes [Pull/Back] LB Rows [All Core] SB Tucks/Pikes Abs: Bikes Scissors Side Plank Ups -Andre Vazquez MAS:FitDre Mobility.Athletics.Strength @FitDre www.fitdre.wordpress.com Become a LIKE
Switchout, 27 May 2011, Fighting Through the Blahs
Switchout Circuit Training
Switchout Circuit Training Arms (3) Triceps – press, dips, kickbacks Legs (3) quads, hams, squats Chest (3) center, lower, upper Shoulders (3) straight, straight, upper flat bench + eagle flies 1×15@bar // 1×10@95 // 2×10@115 + 2×10@5 // 2×10@10 T-handle + tricep press 3×10@45 + 3×10@35 quads + shoulder press 3×10@50 3×10@20 db dips 3×10 hams + kickbacks 3×10@45 + 2×10@15 // 1×10@20 DB incline bench + DB squats 3×10@20 + 3×10@20 Explanation :: The concept behind this exercise strategy is simple; while you are working one body part, the other is resting. There is no rest period between sets. By switching between exercises quickly, your heart rate remains high. This burns calo
One Day at a Time…
The Incredible Shrinking Lady
So yesterday I ran into an old friend of mine, and we went to dinner with our significant others. This was my first time at a restaurant since I started my diet two weeks ago. Background history: before the diet started, I was going out to dinner most nights of the week somewhere, so this diet has significantly reduced my outgoing money on food. (yay!) At the restaurant we had great conversations, and I had my challenges with wanting to eat some of the homemade, honey cornbread that came out on a griddle, but I still made it. Wow! I made it through the whole dinner without taking a bite of anything else. At this moment I am so happy that I had the will-power to do it. At the time last night I was ready to break the diet to have some ‘pownbread. Hindsight is 20/20. Tonight is the end of my 2nd week’s weigh in, and I’m really looking forward to it. Mathematically speaking, I should have lost about 4 lbs this past week with the amount of calories consumed, burnt and expe
A Hard to Swallow Subject
Hollani's Hot Topics
This weekend while cooking for several of my co-workers, I found myself praying, “Please Lord, don’t let this food make them sick!” If you’re like me, your are extremely paranoid with all of these recent food related illnesses. Cantaloupe – Listeria Ground Beef – E. coli (Ground Turkey earlier this year) Lettuce – Listeria Spinach Dip – Listeria Turkey Burgers – Salmonella Strawberries – E. coli Papaya – Salmonella Eggs (2010) – Salmonella It’s really quite scary when you think about it. Especially since I eat all of the foods I listed above. I’m especially bad at eating things with raw eggs in it (cookie dough, brownie batter – yea, I still sneak it a spoonful every now and then). I think about the families who’ve lost someone from one of these tainted products. How devastating is that? “My brother died because he ate cantaloupe for breakfast.” Is this the new norm? Washing food
Prevent breast cancer, with exercise.
Exercise doesn’t just lower the number on the scale, studies now show that it can also reduce breast cancer risk. Click here for more Information.
ACO Roadblocks, Courtesy of CMS
Uncommon Clarity
We recently reviewed an article outlining the current debate between the American Telemedicine Association (ATA) and Centers for Medicare & Medicaid Services (CMS) regarding the statutory restrictions placed on telehealth by CMS in certain rules effecting accountable care organizations (ACOs). In summary, ATA is asking that five Medicare requirements that effectively limit the use of telemedicine—by prohibiting reimbursement—be waived or modified. It is ironic that CMS is supporting unnecessary road blocks to ACO enablement, a care delivery methodology that is a cornerstone of the 2009 health reform legislation. At the core of the government’s support for ACOs is the idea that Medicare and Medicaid spending is unsustainable and a system that rewards providers for delivering the same (or better care) could be most impactful by better managing patients with chronic conditions, reducing readmissions and minimizing ER visits. Thus, it seems counterintuitive that new approaches to d
More from this author
Road Biking Colorado National Monument
SheSpoke. Living her adult childhood
+12 more images
After a decade and a half of strictly mountain biking, I’ve made the transition over to the dark side. A friend of mine lent me her neon yellow Trek from the 1980s, and I’ve been commuting and playing around the urban trails of Denver for a few months now, excited at how light and fast it is. I’ve been a spectating fan of road biking since the early days of Lance, marveling at how anyone can pedal for six hours up and over mountains for well over 100 miles. I’m now starting to get it. Independence Monument, a beautiful product of erosion, in the background These bikes are light, and the pedaling is continuous uphill and you’re coasting downhill. In fact, on the downhill all you’re really worried about is running over a frightened rodent who will then send you flying through the air like the Greatest American Hero(ine). When I started riding 30+ miles on the road bike, (akin to riding 10+ intermediate miles on the mountain bike), I was looking for pai
More from this author
Quiet time on the running trail
Minnesota Transplant
“The gun goes off and everything changes … the world changes … and nothing else really matters.” ~ Patti Sue Plumer, American long-distance runner Running is an effective weight-management tool, and it smooths the rough edges on my stress profile, too. I know for a fact I am bitchier on days I don’t get exercise. When I need quiet time, I put on my Asics and dash out the door. I often run with my iPod, but when I’m in a pickle, I leave it behind and just pound the pavement while I think about my breathing. I distinctly remember a 6-mile run on a summer day five years ago. The day before, I had to lay off two staff members, and it felt like choosing which toes I wanted to have removed. I have no doubt that black day was more awful for the two women I laid off, and I don’t mean to minimize their experiences as I lament my role in middle-management. But (yes, but!) unless you’re Cruella DeVille, telling people you’ve hired and mentored
The Latest Posts in Health Recently posted on WordPress.com Subscribe
Watch the Fine Print When You’re Watching Your Weight
joycemcdonald
It’s okay to go off your diet once in awhile. We all do it now and then. Just be careful not to do it every day or so. Maybe once a week is good for you. The problem may not be how often we fudge a little, but what it is we choose when we cheat. You can stop by Starbucks for a cup of coffee or you can have Starbucks Venti (20 oz.) White chocolate Mocha with 2% milk and whipped cream. If you give in to the Venti, you will be taking on more calories than if you had a McDonald’s Quarter Pounder with Cheese! You would be adding 580 calories and 15 grams of saturated fat. Of course you could have the Venti with non-fat milk and no whipped cream. That would be 130 calories less. Maybe you like Marie Callender’s Chicken Pot Pie. The 16.5 oz. package proudly says “only 520″ calories. If you read carefully that is for only half a pie! Eat the whole thing and you will have consumed 1,040 calories, more than a day’s worth of saturated fat, and an e
Scary, sick voice!!!
My Blogging Path
On Tuesday, October 4, 2011 at 10:38 AM, I received an “Auto-Forwarded voicemail message from (xxx) xxx-xxxx”. And the email showed a “Transcribed Message” that was rated “Good” by me because they didn’t spell my name correctly, one word was incorrect and the rest drifted to incoherence. This is partially because the caller didn’t sound the same! His voice is steady, deeper and scary! It’s sounds congested as if he has a very bad cold in the sinuses. The pattern of his speech and word usage sounded like him. But I have a weird feeling it is NOT his usual “self”. OMG! What’s going on? Is he still really alive? What are you people pulling over my ear holes? Perhaps, he needs your boost/prayer because he has “special gifts”, which I senses/knew/test that we last saw each other in person. Again, his professionalism will be noted (in my “Akashic Book/s of Life”) for returning a long-distant phone
MMR Yet Again
Letting Off Steam
The Daily Mail will not let go of the mythical MMR-autism link. Their writer Sally Beck claims that:- New American research shows that there could be a link between the controversial MMR triple vaccine and autism and bowel disease in children. This is complete bollocks, to use a technical term. First it is not new research. The Times reported it back in 2006. It is instructive to compare the two articles. The Times wrote: The latest study, led by Arthur Krigsman, of New York University School of Medicine, involved 275 children. Serious intestinal inflammations were found in some of the autistic children and biopsies of gut tissue were performed on 82 of them. Of these, 70 are said to have shown evidence of the measles virus, which so far has been confirmed in 14 cases by more stringent DNA tests. Steve Walker, assistant professor at Wake Forest University Medical Centre, North Carolina, who analysed the gut samples, said the work mirrored Dr Wakefield’s study. All the children involved
+4 more images
OBSTACLE COURSE
snowbirdredux
Ice Surfer, Lake Michigan
Great Pictures Collection
Taking a look at eye safety – Part 1
Touching Base
Laura Mercier Tinted Moisturizer
fnkyluda
Better Mood with Singing
+10 more images
Break for Intestines
Green Plate Dinners
Just Live With It: Losing The American Dream
Fidlerten Place
Whatever your political beliefs are, I would ask that you set those aside, if but for a short while. I ask that because I would like to take a moment to talk about the American Dream, which is something I believe that everyone can relate to. Of course, there are as many perceptions of what the American Dream is as there are people dreaming of it. Regardless of how those dreams are realized, I think that at the most basic level, most people seek to have a sense of prosperity, security and well-being. Each generation seeks to be just a bit better off than the one before, and hopes that their children will be just a bit better off still. As far as the American Dream goes, I know that I am very fortunate. Some might even say “blessed”, though that would not be my personal choice of words. I’ve worked hard and graduated college. I have a good job and even own my own home. I am not by any measure “wealthy”. I don’t keep up with the Joneses. But, I certainly do better than my fathe
Eating with Autism-1
Accidental Autism
One of my favorite measures of “well-being” is eating and appetite; when we are happy and contented, most of us enjoy eating and sharing meals with friends and family. When anxiety and depression set in, this simple and universal pleasure is lost to us. A recent piece in the New York Times shows families of all types eating together and enjoying the “feeling that everything is going to be all right, if only for the moment”. The photos are by Stephanie Sinclair and text by Sam Sifton. Our family, like many these days, does not gather together often enough because of international travel for work and the life styles of our extended families. We did recently have my husband and his three siblings gathered in our house and our daughter who has severe autism was able to join us. We had been warned by her staff at her group home that she had been unstable and dangerous after a recent medication change. They advised us not to bring her home for this gathering. What
Housing Priorities for Retiring Baby Boomers – Lifestyle and Health Related Issues Are Most Important
John Murphy Reports
Now that America has exhausted the first time home buyer with the various tax credits, it’s time we switch back to the real movers and shakers in housing – that of course is the massive generation known as the baby boomers. They are starting to retire at a rapid clip and their choices with regard to housing will have a major impact on markets across the U.S. Builder Magazine recently published an interesting article that highlighted some of the results from a baby boomer poll conducted by NPR, The Robert Johnson Foundation and the Harvard School of Public Health, the results of which may be found here. What’s great about the survey is that they break it in to two groups – those who have already retired and those who are still pre-retirement. In many of the questions there is a distinct difference between the two groups. There were notable differences of opinions with regard to good public schools, public transportation, or the ability participate in voluntee
CST#1
FitDre : Mobility.Athletics.Strength (MAS) by Andre Vazquez
If you’re approaching 30 or are already in your 30′s (like me) then you already know you GOTTA train your biggest and baddest muscle of all, YOUR HEART! Push and keep that thing ticking more effectively and efficiently when you most need it. Cardio Strength Training (CST) #1 uses the following template which can later be switched and swapped out for other exercises. It borrows from the book Cardio Strength Training by Robert Dos Remedios (plug). It’s one of my favorite templates to borrow. For this workout everything is 10 reps (change your reps according to your need/goals). You will run through the entire series about 5x in under an hour to burn anywhere from 500-800 calories. [Explode] Single Leg Power Step-Up Jump [Major Hip/Knee] OHP, Step-Up, Rev.Lunge [Push/Chest] Prone MB Passes [Pull/Back] LB Rows [All Core] SB Tucks/Pikes Abs: Bikes Scissors Side Plank Ups -Andre Vazquez MAS:FitDre Mobility.Athletics.Strength @FitDre www.fitdre.wordpress.com Become a LIKE
Switchout, 27 May 2011, Fighting Through the Blahs
Switchout Circuit Training
Switchout Circuit Training Arms (3) Triceps – press, dips, kickbacks Legs (3) quads, hams, squats Chest (3) center, lower, upper Shoulders (3) straight, straight, upper flat bench + eagle flies 1×15@bar // 1×10@95 // 2×10@115 + 2×10@5 // 2×10@10 T-handle + tricep press 3×10@45 + 3×10@35 quads + shoulder press 3×10@50 3×10@20 db dips 3×10 hams + kickbacks 3×10@45 + 2×10@15 // 1×10@20 DB incline bench + DB squats 3×10@20 + 3×10@20 Explanation :: The concept behind this exercise strategy is simple; while you are working one body part, the other is resting. There is no rest period between sets. By switching between exercises quickly, your heart rate remains high. This burns calo
One Day at a Time…
The Incredible Shrinking Lady
So yesterday I ran into an old friend of mine, and we went to dinner with our significant others. This was my first time at a restaurant since I started my diet two weeks ago. Background history: before the diet started, I was going out to dinner most nights of the week somewhere, so this diet has significantly reduced my outgoing money on food. (yay!) At the restaurant we had great conversations, and I had my challenges with wanting to eat some of the homemade, honey cornbread that came out on a griddle, but I still made it. Wow! I made it through the whole dinner without taking a bite of anything else. At this moment I am so happy that I had the will-power to do it. At the time last night I was ready to break the diet to have some ‘pownbread. Hindsight is 20/20. Tonight is the end of my 2nd week’s weigh in, and I’m really looking forward to it. Mathematically speaking, I should have lost about 4 lbs this past week with the amount of calories consumed, burnt and expe
A Hard to Swallow Subject
Hollani's Hot Topics
This weekend while cooking for several of my co-workers, I found myself praying, “Please Lord, don’t let this food make them sick!” If you’re like me, your are extremely paranoid with all of these recent food related illnesses. Cantaloupe – Listeria Ground Beef – E. coli (Ground Turkey earlier this year) Lettuce – Listeria Spinach Dip – Listeria Turkey Burgers – Salmonella Strawberries – E. coli Papaya – Salmonella Eggs (2010) – Salmonella It’s really quite scary when you think about it. Especially since I eat all of the foods I listed above. I’m especially bad at eating things with raw eggs in it (cookie dough, brownie batter – yea, I still sneak it a spoonful every now and then). I think about the families who’ve lost someone from one of these tainted products. How devastating is that? “My brother died because he ate cantaloupe for breakfast.” Is this the new norm? Washing food
Prevent breast cancer, with exercise.
Exercise doesn’t just lower the number on the scale, studies now show that it can also reduce breast cancer risk. Click here for more Information.
ACO Roadblocks, Courtesy of CMS
Uncommon Clarity
We recently reviewed an article outlining the current debate between the American Telemedicine Association (ATA) and Centers for Medicare & Medicaid Services (CMS) regarding the statutory restrictions placed on telehealth by CMS in certain rules effecting accountable care organizations (ACOs). In summary, ATA is asking that five Medicare requirements that effectively limit the use of telemedicine—by prohibiting reimbursement—be waived or modified. It is ironic that CMS is supporting unnecessary road blocks to ACO enablement, a care delivery methodology that is a cornerstone of the 2009 health reform legislation. At the core of the government’s support for ACOs is the idea that Medicare and Medicaid spending is unsustainable and a system that rewards providers for delivering the same (or better care) could be most impactful by better managing patients with chronic conditions, reducing readmissions and minimizing ER visits. Thus, it seems counterintuitive that new approaches to d
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